Recent publications from the Weiss Lab

Recent patents from the Weiss Lab

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Weiss Lab

Location: Charles Perkins Centre D17

University of Sydney, NSW, 2006, Australia

Telephone: +61 2 93513464

Regeneration of damaged tissue, US11,084,867

Scalable three-dimensional elastic construct manufacturing, US11,077,226

​Regeneration of damaged tissue, AU2019204972B2

​In vivo synthesis of elastic fiber, AU2019204915B2

​Tropoelastin for use in inducing formation of bone, EP3344280B1

​Formation of bone, US10,736,942​​​​

​Bioactive polymer for bone regeneration, AU2016314146B2​

• Hume, R.D., Kanagalingam, S., Deshmukh, T., Chen, S., Mithieux, S.M., Rashid, F., Roohani, I., Lu, J., Doan, T., Graham, D., Clayton, Z.E., Slaughter, E., Kizana, E., Stempien-Otero, A.S., Brown, P., Thomas, L., Weiss, A.S. and Chong, J.J.H. (2023) Tropoelastin improves post-infarct cardiac function. Circ Res. 132, 72–86.
  
• Zhang, M., Wang, Z., Zhang, A., Liu, L., Mithieux, S.M., Bilek, M.M. and Weiss, A.S. (2023) Development of tropoelastin-functionalized anisotropic PCL scaffolds for musculoskeletal tissue engineering. Regen. Biomat. 10, rbac087.
  
• Yang, C., Weiss, A.S. and Tarakanova, A. (2023) Changes in elastin structure and extensibility induced by hypercalcemia and hyperglycemia. Acta Biomaterialia . 163, 131-145.
  
• Wang, Z., Mithieux, S.M., Vindin, H., Wang, Y., Zhang, M., Liu, L., Zbinden, J., Blum, K.M., Yi, T., Matsuzaki, Y., Oveissi, F., Akdemir, R., Lockley, K.M., Zhang, L., Ma, K., Guan, J., Waterhouse, A., Pham, N.T.H., Hawkett, B.S., Shinoka, T., Breuer, C.K. and Weiss, A.S. (2022) Rapid regeneration of a neoartery with elastic lamellae. Adv. Mat. 2205614.
• Al Halawani, A., Mithieux, S.M., Yeo, G.C., Beheshti, E.H. and Weiss, A.S. (2022) Extracellular vesicles: interplay with the extracellular matrix and modulated cell responses. Int. J. Mol. Sci. 23, 3389, 1-11.
  
• Roohani, I., Yeo, G.C., Mithieux, S.M. and Weiss, A.S. (2022) Emerging concepts in bone repair and the premise of soft materials. Curr. Opin. Biotech 74, 220-229.
  
• Vindin, H.J., Oliver, B.G.G. and Weiss, A.S. (2022) Elastin in healthy and diseased lung. Curr. Opin. Biotech 74, 15-20.
  
• Al Halawani, A., Abdulkhalek, L., Mithieux, S.M. and Weiss, A.S. (2021) Tropoelastin promotes the formation of dense, interconnected endothelial networks. Biomolecules, 11, 1318, 1-12.
  
• Bax, D.V., Nair, M., Weiss, A.S., Farndale, R.W., Best, S.M. and Cameron, R.E. (2021) Tailoring the biofunctionality of collagen biomaterials via tropoelastin incorporation and EDC-crosslinking. Acta Biomaterial. 135, 150-163.
  
• Alanazi, Y. F., Lockhart-Cairns, M.P., Cain, S.A., Jowitt, T.A., Weiss, A.S. and Baldock, C. (2021) Autosomal recessive cutis laxa 1c mutations disrupt the structure and interactions of latent TGFβ binding protein-4. Frontiers Genet. 12, 706662, 1-15.
  
• Al Halawani, A., Wang, Z., Liu, L., Zhang, M. and Weiss, A.S. (2021) Applications of engineering techniques in microvasculature design. Frontiers Cardiovasc. Med. 8, 660958, 1-9.
  
• Ozsvar, J., Wang, R., Tarakanova, A., Buehler, M.J. and Weiss, A.S. (2021) Fuzzy binding model of molecular interactions between tropoelastin and integrin alphaVbeta3. Biophys. J. 120, 3138-3151.
  
• Ozsvar, J., Yang, C., Cain, S.A., Baldock, C., Tarakanova, A. and Weiss, A.S. (2021) Tropoelastin and elastin assembly. Front. Bioeng. Biotech. 9, 643110, 1-11.
  
• Bochicchio, B., Yeo, G.C., Lee, P., Emul, D., Pepe, A., Laezza, A., Ciarfaglia, N., Quaglino, D. and Weiss, A.S. (2021), Domains 12 to 16 of tropoelastin promote cell attachment and spreading through interactions with glycosaminoglycan and integrins alphaV and alpha5beta1. FEBS J. 288, 4024-4038.
  
• Baumann, L., Bernstein, E.F., Weiss, A.S., Bates, D, Humphrey, S., Silberberg, M. and Daniels, R. (2021) Clinical relevance of elastin in the structure and function of skin. Aesthet. Surg. J. Open Forum. 3, ojab019.
  
• Wang, Z., Liu, L., Mithieux, S.M. and Weiss, A.S. (2021) Fabricating organized elastin in vascular grafts. Trends Biotech. 39, 505-518. 
  
• Almeida-González, F.R., González-Vázquez, A., Mithieux, S.M. O’Brien, F.J., Weiss, A.S. and Brougham, C.M. (2021) A step closer to elastogenesis on demand; inducing mature elastic fibre deposition in a natural biomaterial scaffold. Mat. Sci. Eng. 120, 111788, 1-12.
  
• Mitzmacher M.G., Mithieux, S.M., Weiss, A.S., Hee, C.K. and Daniels, R. (2020) Novel recombinant tropoelastin implants restore skin extracellular matrix. J. Drugs Dermatol. 19, 1166-1172.​